The build which is mainly used to make intensive deep learning computations is featuring a AMD threadripper 3970X in combination with 256Gb of RAM 3600MHz, two Nvidia Titan RTX +NVLink. The whole stuff is mounted on a Asus Zenith ii extreme alpha motherboard. MyDeep is running under both Windows 10 / PopOs environments installed on separate Samsung 970 Evo plus 2TB SSD's. The concept was first to create two independent water loops to cool the CPU, the GPU's and the motherboard. Dues to spacing contraints- yes even with a Phanteks Enthoo Elite - the plan was updated and transformed into a hybrid serial/parallel dual loop featuring 3 radiators as well as 17 Phanteks/EKWB 140mm fans. Here is a brief description of the cooling paths A and B A Phantek glacier distro plate is collecting the return path of both CPU and GPU's water blocks and send the water to the top radiator 1 (Alphacool NexXxos ST30 XFlow 420mm, 3 EKWB 140mm fans in push mode) After radiator 1, the water is driven into the front radiator 2 (EK-CoolStream SE 560mm, 4 EKWB 140mm fans in pull mode) the water path splits into two sub-loops: one loop A for the CPU and the other loop B for the GPU's CPU Loop A heads to the vertical tank (EK-Quantum Kinetic TBE 300 D5 PWM) make a bend under a horizontal separation plate and plugs into the inputs of the Phanteks distro which itself is connected to the CPU/motherboard EK quantum Zenith II waterblock GPU's Loop B crosses the bottom radiator 3 (Alphacool NexXxos XT45 XFlow 420mm, 3 + 3 fans in push-pull mode) and head to the horizontal tank (EK-Quantum Kinetic TBE 300 D5 PWM) which itself connects to the EK-Scalar Dual 3-slot of the GPU's. Loop B ends by connecting to the distro plate return path 3 EK-Vardar X3M 120mm fans mounted on a side plate are also running behind the vertical tank in a pull mode. The complete loop is about 2,5 liters of water that runs quite smoothly. Some additional rubber was used to damp vibration induced in both tanks. MyDeep is actually a beast for intensive GPU computations.