First time messing with clock/voltage settings. Didn't go too crazy. Didn't go past 5.0Ghz CPU but I believe I probably could've. I've been playing a lot of Destiny 2 lately so I got a little light!
Before I had to route the GPU cables over the tube above it but found 180 degrees 8-pin adapters on amazon. Cleans up the cabling and works well. I switched from a header powered DDC pump to a Molex powered one recently. Luckily didn't have to re-sleeve the cables for aesthetics for the frontal view. Custom length power cables make things easier.
The side panels have plenty of perforation so I'm skipping the TG panel mod. I'm going to add in an extra Noctua NF-A12x15 or Noctua NF-A9x14 for side intake. The temp difference might be negligible but the DDC pump with heat sink needs airflow over it. The VRMs are okay but it would help there too.

CPU was delidded and TIM switched to Conductonaut.
CPU benchmarks were done using x264. GPU benchmarks were done using Heaven 4.0 and real-world testing on Destiny 2 and The Outer Worlds.

Ambient Temperature
20.55c
Idle
CPU 38c
GPU 33c

STOCK x264 test
Min 38c
Max 63c
Average 59c

Stock clock -0.07v offset
Min 31c
Max 52c
Average 48c

4.9GHz 1.232v
Min 34c
Max 62c
Average 59c

5.0GHz 1.300v
Min 34c
Max 69c
Average 67c

GPU Benchmark Heaven 4.0
+165 Core/+1100 Memory
2265Mhz Core/ 8100 Mhz Memory
Min 32c
Max 47c
Average 40c

Destiny 2 and The Outer Worlds
CPU 58c-68c depending on what I'm looking at in-game.
GPU 53c-57c