In terms of components, I've replaced the original build's Ryzen 9 3900X with the newer 5900X CPU, added an additional 500GB Samsung 970 Evo Plus NVME for Linux dual booting, vertically mounted the GPU, and replaced the white and black Corsair sleeved PSU cables that had started to turn an odd pinkish color with custom length purple and white CableMod Pro ModMesh cables.
The changes to the loop itself, however, are more drastic. I've replaced the EKWB FLT 360 resovoir-pump combo with a dual-pump side panel distribution plate from WV Mech and added two Aquacomputer D5 NEXT Pumps. While the original loop was built with Corsair's 12mm clear acrylic tubing, the redone version uses Corsair's 12mm satin transparent acrylic which provides a frosted look and gives the colored coolant a more vibrant appearance. I've also repainted the original radiators and fittings to make them more consistent with the overall theme.
As far as performance, the 5900X provides some pretty sizable speed gains over the 3900X it replaced. I plan on swapping out the 2070 Super for either an RTX 3080TI or RTX 3090 for added computational power since the system's primary use is bayesian inference.