I had this in a Phanteks Evol ITX with a thin XSPC 240mm radiator and a Bitspower Hexagon reservoir but I didn't like the way the tubes were run so I bought this 280x. After a long day of planning, I realized my 2nd radiator wouldn't fit due to thickness of the nemesis without just being passive. With that being an issue the reservoir also wouldn't fit natively or having to flip the system so a right angle fitting is my fill port. The only regret is I don't have more servo fans or a Gene board.